E-crotylboron pinacolate - Names and Identifiers
Name | trans-Crotylboronic acid pinacol ester
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Synonyms | trans-CrotyL E-crotylboron pinacolate trans-Crotylboronic acid pinacol ester trans-Crotylboronic acid pinacol ester 2-[(2E)-2-Buten-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1,?3,?2-?Dioxaborolane, 2-?(2E)?-?2-?buten-?1-?yl-?4,?4,?5,?5-?tetramethyl- E-Crotylboronic acid pinacol ester, trans-2-(2-Buten-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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CAS | 69611-02-5
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E-crotylboron pinacolate - Physico-chemical Properties
Molecular Formula | C10H19BO2
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Molar Mass | 182.07 |
Density | 0.888 g/mL at 25 °C |
Boling Point | 68-76 °C(Press: 7 Torr) |
Flash Point | 63°C |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.434 |
E-crotylboron pinacolate - Risk and Safety
UN IDs | NA 1993 / PGIII |
WGK Germany | 3 |
E-crotylboron pinacolate - Introduction
trans-Crotylboronic acid pinacol ester is an organic compound with the chemical formula C10H17BO2. It is a clear and colorless liquid, stable at room temperature and pressure.
trans-Crotylboronic acid pinacol ester has a wide range of applications in organic synthesis. It can be used as a reagent in organic synthesis to participate in a variety of chemical reactions, such as reduction reactions, coupling reactions and carbonylation reactions. Specifically, it can be used as a reducing agent for aldehydes and ketones for the synthesis of alcohol compounds; it can also be used as a ligand to participate in metal-catalyzed reactions for the construction of chemical bonds; in addition, it can also be used for the synthesis of complex organic molecules, such as natural products and drugs.
the preparation of trans-Crotylboronic acid pinacol ester is mainly obtained by reacting crotyl lithium (chemical formula LLi) with triacetylacetone (chemical formula PINACOLONE, an organic synthesis reagent). The specific step is to react crotyl lithium with triacetylacetone at low temperature to generate trans-crotyl lithium salt (chemical formula is LiLLi), and then react with boric acid substitution agent to obtain trans-Crotylboronic acid pinacol ester.
For safety information, trans-Crotylboronic acid pinacol ester is an organic compound, routine laboratory safety operations should be followed. It is irritating to the eyes and skin and may cause irritation to the respiratory system. Wear protective goggles, lab gloves and lab coats during use. In case of accidental contact, flush immediately with plenty of water and seek medical help. In the process of preservation and handling, should be away from fire and flammable substances, stored in a dry, cool place.
Last Update:2024-04-09 20:49:11